Research Technology & Consulting for better life
Research Technology & Consulting for better life
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As a young boy growing up in rural India, most of what I knew of the world was what I could see around me. But each night, I would look at the Moon...
NATURE INDIA | INDIGENUS
Away from home: Using science for societal good
Imagine a world where hospitals only exists for intensive care, surgery and other procedures. There would be fewer visits to doctors' offices as well. All monitoring would be done at home. Scripps Health's Dr. Topol, says this future is closer than we think. He discussed part of the Precision Medicine Initiative (All of Us Research Program), a one million American prospective research program.
Aravinda Chakravarti, PhD, a nationally renowned geneticist, will join the faculty of NYU Langone Health on April 2 as director of its new Center for Human Genetics and Genomics
Welcome to Mattapally Technologies research page.
I am Mattapally Saidulu working as a Founder & CEO at the Mattapally Technologies
My main research interests are Biomedical Engineering, Pulmonary Cardiac Regeneration, Universal Cells, Molecular Genetics.
Summary of my research:
Currently, hiPSCs with knockout mutations for Per1, Per2, CIITA, B2M, N-Cadherin, Connexin43 and Overexpression of Connexin43 have been produced utilizing CRISPR/Cas9 gene-editing technology. hiPSCs were used to generate cardiomyocytes (CM), and spheroid culture was used to elucidate the circadian rhythms in hiPSCs differentiated cardiomyocytes . Research mainly focused on Stem cells, cell differentiation, dedifferentiation, Congenital Heart Disease, Diabetic Cardiomyopathy, Pharmacology, Molecular Genetics, and Pulmonary Cardiac Regeneration.
Please click the headers below for more information about me
Abstract in Journals:
Patent Granted/Filed (US, French & India):
1. Mahendar B, Mattapally S, Ravinder M, Banerjee SK, Rao VJ. Pyridopyrimidine based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof. US Patent App. 14/168,411, 2014.( US20140221651 A1 ) patent/US9242982B2/en
2. Mahendar B, Mattapally S, Ravinder M, Banerjee SK, Rao VJ. Indolizinone based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof. US Patent App. 14/168,370, 2014.( US20140296530 A1 ) patent/US9249139B2/en
3. Mahendar B, Mattapally S, Ravinder M, Banerjee SK, Rao VJ. Pyridopyrimidine based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof. IN Patent App. 287/DEL/2013.
4. Mahendar B, Mattapally S, Ravinder M, Banerjee SK, Rao VJ. Indolizinone based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof. IN Patent App. 288/DEL/2013.
5. G. Jagadeesh KUMAR, B. Mahendar, M. Saidulu, S K Banerjee, V. Jayathirtha RAO. 2-pyridone based compounds useful as potential phosphodiesterase3a (pde3a) inhibitors and a process for the preparation thereof. WO2017072796A1 (USA, French). patent/WO2017072796A1/en
Book Chapter:
1. Mattapally S, Cukier-Meisner W.K, Zhang J. (2017) Differentiation and Use of Induced Pluripotent Stem Cells for Cardiovascular Therapy and Tissue Engineering. In: Ieda M., Zimmermann WH. (eds) Cardiac Regeneration. Cardiac and Vascular Biology. Springer. DOI https://doi.org/10.1007/978-3-319-56106-6_5.
I am currently worked on the project “COVID-19 role immunosuppresion and arrhythmias in solid-organ transplant recipient.”
The project involves understanding the clinical highlights and results of COVID-19 among immunosuppressed patients, who are at assumed risk of more serious infection.....
Your support and contributions will enable us to meet our goals and improve conditions. Your generous donation will fund our mission.
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Based on my expertise from original research publications in world-class peer reviewed
Journals and invited talks at international conferences, I was invited to be an
Research interest:
Molecular Genetics; Biomedical Engineering; Pulmonary Cardiac Regeneration; Universal Cells
Complete List of Published Work
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